Hi. You asked for my email. I cancelled my question before I saw


Question Description:

35

Hi. You asked for my email. I cancelled my question before I saw your response. My email is m..2@yahoo.com. ATTACHMENT PREVIEW Download attachment Problem_Set_3.doc Human Genetics BIO 104 Problem Set 3 Name: ______________________ 1. An estimate of the likelihood of recurrence based on population statistics for similar individuals in the population is called _____________________________. (1 point) 2. Heritability is an estimate of_____________________________________________ ____________________________________________________________. (1 point) 3. Blood pressure is influenced by both genetic and environmental factors. In a study of sibling pairs, both siblings of the pair had high blood pressure in 30% of the pairs. What is the heritability of this trait? SHOW ALL WORK! (2 points) 4. Complete Applied Question 1 in Chapter 5 on page 107 of the textbook. (9 points) a) b) c) d) e) f) g) h) i) 2 5. Cleft lip (failure of the upper lip to fuse) and cleft palate (failure of the soft palate to fuse) are multifactorial conditions that occur during prenatal development. More than 200 syndromes include cleft lip with or without cleft palate. When clefts occur alone, individuals with an affected relative have an increased risk of being born with a cleft. Empiric risk of recurrence depends upon the degree of relationship to an affected individual as follows: • If one parent has a cleft, risk to a child is 4%. • If one sibling has a cleft, risk to another sibling is 4%. • If two siblings have a cleft, risk to a third sibling is 9%. • If one parent and one sibling have a cleft, risk to another sibling is 17%. In each family depicted in (a) through (e), a couple expecting a child is concerned that the child will have a cleft lip with or without cleft palate. For each couple, cite the risk that the fetus (designated as a diamond) faces. Be sure to consider all relatives shown. (6 points) (a) _______ (b) _______ (c) _______ (d) _______ (e) _______ 3 6. Maple syrup urine disease (MSUD) is an autosomal recessive inborn error of metabolism that causes mental and physical retardation, difficulty feeding, and a sweet odor in urine. In Costa Rica, 1 in 8,000 newborns inherits the condition. Calculate the carrier frequency of MSUD in this population. (4 points) 7. Duchenne muscular dystrophy is an X-linked recessive disorder that occurs in about 1 out of every 3,500 male births. How many females would be expected to have this disorder? (2 points) 8. The carrier frequency of cystic fibrosis in American Caucasians is approximately 1/25. Two individuals from this population, neither of whom have a family history of the disorder, have a child together. What is the probability that the child has cystic fibrosis? (2 points) 9. A man, blood type B, tells his wife he wants a divorce after she has a baby with blood type O. He says he cannot possibly be the father. Is he correct? _______ Draw one or more Punnett squares to support your answer. (2 points) 4 10. According to this pedigree, exactly how are Maxi and BJ related? (1 point) Tanya Tony Frisco BJ 11. Felicia Maxi Consider the following pedigree and determine whether the pattern of inheritance is more likely to be autosomal dominant, autosomal recessive, X-linked dominant, X-linked recessive or mitochondrial. Explain your response. (2 points) 5 Read more

Answer

35