Coupling ATP hydrolysis to a thermodynamically unfavorable reaction can shift the equilibrium of a reaction. Calculate K for the hypothetical reaction A–> B when Delta G is 23 kJ/molat 25 C. Calculate K for the same reaction when it is coupled to the hydrolysis of ATP (Delta G = -30 kJ/mol.,Q. Many cells maintain ATP to ADP ratios of 400 or more. Calculate the ratio of B to A when ATP/ADP = 470 and Pi = 5 mM. A and B mentioned above is of previous problem solved by you. Q. Compare this ratio to that for the uncoupled reaction.