14. The mutation causing the recessive disease allele for


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14. The mutation causing the recessive disease allele for sickle-cell anemia removes one MstII restriction site from the globin gene so that a probe, instead of hybridizing to two fragments of 1.1 kb and 0.2 kb, hybridizes to one 1.3-kb fragment. For two parents to have a 25 percent chance of a child with sickle-cell anemia A) they must both show only fragments of 1.1 and 0.2 kb. B) they must both show fragments of 1.3 and 0.2 kb. C) one must show only a 1.1- and the other only a 0.2-kb fragment. D) one must show a 1.3- and the other a 1.1- and a 0.2-kb fragment. E) they must both show all three types of fragments.

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